Cutaneous squamous cell carcinoma in Calabar, southern Nigeria
| Autor: | E. E. Bassey, Godwin Ebughe, A M Udosen, Ngim E. Ngim, Ikpeme A. Ikpeme, Maurice E. Asuquo, Otei O. Otei |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Health Knowledge Attitudes Practice medicine.medical_specialty Skin Neoplasms Adolescent Albinism medicine.medical_treatment Nigeria Skin Pigmentation Dermatology Lesion Young Adult Pharmacotherapy Risk Factors Internal medicine Prevalence medicine Skin Squamous Cell Carcinoma Humans business.industry Cancer Middle Aged Prognosis medicine.disease Surgery Radiation therapy Latency stage Carcinoma Squamous Cell Female Skin cancer medicine.symptom business |
| Zdroj: | Clinical and Experimental Dermatology. 34:870-873 |
| ISSN: | 1365-2230 0307-6938 |
| DOI: | 10.1111/j.1365-2230.2009.03243.x |
| Popis: | Summary Background. Several studies have shown that in Africa squamous cell carcinoma (SCC) is commoner than other skin malignancies. The risk factors are grouped generally into solar and nonsolar factors and their contributions vary with race, geographical region and site of lesion. This study attempted to identify risk factors and outcome of management of this problem in our region of southern Nigeria. Methods. All patients with histological diagnosis of SCC presenting to the University of Calabar Teaching Hospital during the period January 2005 to December 2006 were evaluated. Results. In total, 10 patients (6 male, 4 female, mean age 39.3 years, range 16–62) were seen. There were six patients (60%) with Marjolin’s ulcer (MU) of the leg, with a male : female ratio of 5 : 1 and a latency period of 14.7 years, with trauma as the leading cause of injury. The other four patients (40%) had non-MU SCC. Two of these four patients (one man, one woman) were albino, and had lesions that involved the head. The other two patients were both women, and had vulval lesions. All 10 patients had delayed hospital admission, after poor results with topical herbal treatment. After hospital treatment, the results were satisfactory in three patients (two with MU and the male albino patient). The other seven patients had generally poor results from treatment, which comprised various combinations of excision, adjuvant chemotherapy and radiation. Conclusion. Ignorance and sociocultural factors were underlying issues in delaying treatment. Education highlighting the risk associated with chronic wounds and albinism, and the need for prevention, prompt treatment and proper surgical management, would improve prognosis with a reduction in the healthcare cost of this problem. |
| Databáze: | OpenAIRE |
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