Caenorhabditis elegans as a Model To Determine Fitness of Antibiotic-Resistant Salmonella enterica Serovar Typhimurium
| Autor: | Wilhelm Paulander, Alexandra A. L. Pennhag, Dan I. Andersson, Sophie Maisnier-Patin |
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| Rok vydání: | 2007 |
| Předmět: |
Salmonella typhimurium
Pharmacology Serotype Salmonella Infections Animal biology medicine.drug_class Antibiotics biology.organism_classification Enterobacteriaceae Microbiology Disease Models Animal Mice Infectious Diseases Antibiotic resistance Mechanisms of Resistance Salmonella enterica Drug Resistance Multiple Bacterial medicine Animals Pharmacology (medical) Caenorhabditis elegans Bacteria Antibacterial agent |
| Zdroj: | Antimicrobial Agents and Chemotherapy. 51:766-769 |
| ISSN: | 1098-6596 0066-4804 |
| DOI: | 10.1128/aac.00615-06 |
| Popis: | We used the ability of Salmonella enterica serovar Typhimurium to colonize the gut of Caenorhabditis elegans to measure the fitness costs imposed by antibiotic resistance mutations. The fitness costs determined in the nematode were similar to those measured in mice, validating its use as a simple host model to evaluate bacterial fitness. |
| Databáze: | OpenAIRE |
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