Two cases of malignant struma ovarii with metastasis to pelvic bone
| Autor: | Runhua Hou, Muhammad Z. Shrayyef, Vaseem U. Chengazi, Ismary O De Castro, Rachel A Steinman, Steven D. Wittlin, Paul Van Der Sloot, Stephen R. Hammes, Laura M. Calvi, Ellen Giampoli |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Ovariectomy Bone Neoplasms Hysterectomy Multimodal Imaging Papillary thyroid cancer Metastasis Salpingectomy Young Adult medicine Humans Whole Body Imaging Pelvic Bones Pelvis Gynecology Ovarian Neoplasms Struma ovarii business.industry Thyroidectomy Obstetrics and Gynecology Bone metastasis Malignant Struma Ovarii Middle Aged medicine.disease Magnetic Resonance Imaging Struma Ovarii medicine.anatomical_structure Reproductive Medicine Positron-Emission Tomography Pelvic tumor Female Radiology business Tomography X-Ray Computed |
| Zdroj: | Gynecologic and obstetric investigation. 75(2) |
| ISSN: | 1423-002X |
| Popis: | Histologically, malignant struma ovarii metastasizes rarely, and only a few cases reported bone metastasis. Here, we describe 2 cases of biologically malignant struma ovarii with pelvic bone metastasis. Case 1 is a 22-year-old female who was found to have a large left ovarian mass during routine prenatal ultrasound. Papillary thyroid cancer arising in struma ovarii was identified after laparoscopic salpingo-oophorectomy. After total thyroidectomy, radioactive iodine whole-body scan revealed extrathyroidal iodine uptake in left anterior pelvis. Subsequent I-131 treatment resolved the pelvic metastasis. Case 2 is a 49-year-old female who was diagnosed with malignant struma ovarii in 1996 and presented in 2007 with pelvic recurrence and extensive left hip metastasis. Treatment with resection of the pelvic tumor, total thyroidectomy, and multiple I-131 ablation led to eventual resolution of the abdominal and left hip foci. In conclusion, we present 2 rare cases of malignant struma ovarii, both with metastasis to the pelvic bone. This report makes pelvic bone the most frequent site for bone metastasis in malignant struma ovarii. It also emphasizes the importance of total thyroidectomy in allowing identification and treatment of bony metastasis with radioactive iodine. |
| Databáze: | OpenAIRE |
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