Respiratory Health and Urinary Trace Metals among Artisanal Stone-Crushers: A Cross-Sectional Study in Lubumbashi, DR Congo
| Autor: | Irene Kabange Umba, Sébastien Mbuyi-Musanzayi, Benoit Nemery, Célestin Banza Lubaba Nkulu, Patrick D. M. C. Katoto, Tim S. Nawrot, Cyrille Katshiez Nawej, Paul Musa Obadia, Patient Nkulu Banza, Tony Kayembe-Kitenge, Georges Kalenga Ilunga, Vincent Haufroid |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Vital capacity Lubumbashi respiratory health Cross-sectional study Health Toxicology and Mutagenesis spirometry lcsh:Medicine Urine 010501 environmental sciences mining 01 natural sciences Pulmonary function testing 0302 clinical medicine Medicine Respiratory system Public Environmental & Occupational Health mineral dust medicine.diagnostic_test Dust WORKERS 030210 environmental & occupational health PREVALENCE LUNG-FUNCTION Democratic Republic of the Congo QUARTZ Life Sciences & Biomedicine GUJARAT Spirometry FORCED EXPIRATORY VOLUME Zambia Environmental Sciences & Ecology Article 03 medical and health sciences Environmental health Occupational Exposure Humans metal biomonitoring EXPOSURE SILICA 0105 earth and related environmental sciences Science & Technology business.industry lcsh:R Public Health Environmental and Occupational Health PULMONARY-FUNCTION Odds ratio Confidence interval Cross-Sectional Studies CRUSHING UNITS business Environmental Sciences |
| Zdroj: | International Journal of Environmental Research and Public Health, Vol 17, Iss 9384, p 9384 (2020) International Journal of Environmental Research and Public Health Volume 17 Issue 24 |
| Popis: | Background: Thousands of artisanal workers are exposed to mineral dusts from various origins in the African Copperbelt. We determined the prevalence of respiratory symptoms, pulmonary function, and urinary metals among artisanal stone-crushers in Lubumbashi. Methods: We conducted a cross-sectional study of 48 male artisanal stone-crushers and 50 male taxi-drivers using a standardized questionnaire and spirometry. Concentrations of trace metals were measured by Inductively Coupled - Plasma Mass Spectrometry (ICP-MS) in urine spot samples. Results: Urinary Co, Ni, As, and Se were higher in stone-crushers than in control participants. Wheezing was more prevalent (p = 0.021) among stone-crushers (23%) than among taxi-drivers (6%). In multiple logistic regression analysis, the job of a stone-crusher was associated to wheezing (adjusted Odds Ratio 4.45, 95% Confidence Interval 1.09&ndash 18.24). Stone-crushers had higher values (% predicted) than taxi-drivers for Forced Vital Capacity (105.4 ± 15.9 vs. 92.2 ± 17.8, p = 0.048), Forced Expiratory Volume in 1 Second (104.4 ± 13.7 vs. 88.0 ± 19.6, p = 0.052), and Maximum Expiratory Flow at 25% of the Forced Vital Capacity (79.0.1 ± 20.7 vs. 55.7 ± 30.1, p = 0.078). Conclusion: Stone-crushers were more heavily exposed to mineral dust and various trace elements than taxi-drivers, and they had a fourfold increased risk of reporting wheezing, but they did not have evidence of more respiratory impairment than taxi-drivers. |
| Databáze: | OpenAIRE |
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