Ethnicity and Risk of Hospitalization for Asthma and Chronic Obstructive Pulmonary Disease
| Autor: | Arthur L. Klatsky, Natalia Udaltsova, H. Nicole Tran, Stanton Siu, Carlos Iribarren |
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| Rok vydání: | 2011 |
| Předmět: |
Male
medicine.medical_specialty Alcohol Drinking Epidemiology Black People California White People Body Mass Index Cohort Studies Pulmonary Disease Chronic Obstructive Sex Factors Asian People Risk Factors Internal medicine Humans Medicine Asthma COPD business.industry Proportional hazards model Confounding Age Factors Hispanic or Latino Middle Aged medicine.disease respiratory tract diseases Hospitalization Relative risk Physical therapy Educational Status Female business Body mass index Cohort study |
| Zdroj: | Annals of Epidemiology. 21:615-622 |
| ISSN: | 1047-2797 |
| DOI: | 10.1016/j.annepidem.2010.10.015 |
| Popis: | Purpose To identify ethnic differences for risk of hospitalization for asthma and chronic obstructive pulmonary disease (COPD). Methods We undertook a cohort study with 126,019 participants: 55% whites, 27% blacks, 11% Asians, and 4% Hispanics. To estimate asthma and COPD risk, we used Cox proportional hazards models adjusted for age, sex, body mass index, education, smoking, and alcohol intake. End points were hospitalizations for asthma or COPD. Results Compared with whites, relative risks (RR) with 95% confidence intervals (95% CI) for asthma among other groups were: blacks, 1.7 (1.4–2.0); Hispanics, 0.9 (0.6–1.4); and Asians, 1.6 (1.2–2.1). Among Asians, increased risk was concentrated in Filipino men and women and South Asian men. For COPD, whites were at highest risk; RR of blacks was 0.9 (0.7–1.0); Hispanics, 0.6 (0.3– 0.9); and Asians, 0.4 (0.3–0.6). COPD risk among Asians was lowest in Chinese with RR of 0.3 (0.1–0.5). Conclusions Ethnic disparities in risk of asthma and COPD as well as between both diseases exist, especially for Asian Americans, who have high asthma risk and low COPD risk. While residual confounding for smoking or other environmental factors could be partially responsible, genetic factors in Asians may be involved in decreased COPD risk. |
| Databáze: | OpenAIRE |
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