How and why does the endoplasmic reticulum move?

Autor:	Becky Bola, Viki Allan
Rok vydání:	2009
Předmět:	Molecular Motor Proteins Endoplasmic reticulum Cell Cycle Dynein STIM1 Biology Endoplasmic Reticulum Actin cytoskeleton Microtubules Biochemistry Cell biology Protein Transport Cell Movement Microtubule Organelle Animals Humans Kinesin Cytoskeleton Actin
Zdroj:	Biochemical Society Transactions. 37:961-965
ISSN:	1470-8752 0300-5127
Popis:	The ER (endoplasmic reticulum) is a fascinating organelle that is highly dynamic, undergoing constant movement and reorganization. It has many key roles, including protein synthesis, folding and trafficking, calcium homoeostasis and lipid synthesis. It can expand in size when needed, and the balance between tubular and lamellar regions can be altered. The distribution and organization of the ER depends on both motile and static interactions with microtubules and the actin cytoskeleton. In the present paper, we review how the ER moves, and consider why this movement may be important for ER and cellular function.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41f59542a5277c7b5e11a4a38778685c https://doi.org/10.1042/bst0370961 Zobrazit plný text záznamu