Mechanical Thrombectomy for Acute Ischemic Stroke in Metastatic Cancer Patients: A Nationwide Cross-Sectional Analysis
| Autor: | Hassan Aboul-Nour, Ahmed Maraey, Ammar Jumah, Mahmoud Khalil, Ahmed M. Elzanaty, Hadeer Elsharnoby, Fawaz Al-Mufti, Alex Bou Chebl, Daniel J. Miller, Stephan A. Mayer |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Journal of Stroke. 25:119-125 |
| ISSN: | 2287-6405 2287-6391 |
| Popis: | Background and Purpose Mechanical thrombectomy (MT) is the standard treatment for large vessel occlusion (LVO) acute ischemic stroke. Patients with active malignancy have an increased risk of stroke but were excluded from MT trials.Methods We searched the National Readmission Database for LVO patients treated with MT between 2016–2018 and compared the characteristics and outcomes of cancer-free patients to those with metastatic cancer (MC). Primary outcomes were all-cause in-hospital mortality and favorable outcome, defined as a routine discharge to home (regardless of whether home services were provided or not). Multivariate regression was used to adjust for confounders.Results Of 40,537 LVO patients treated with MT, 933 (2.3%) had MC diagnosis. Compared to cancer-free patients, MC patients were similar in age and stroke severity but had greater overall disease severity. Hospital complications that occurred more frequently in MC included pneumonia, sepsis, acute coronary syndrome, deep vein thrombosis, and pulmonary embolism (P |
| Databáze: | OpenAIRE |
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