The healing response of LAMax LAAC™ left atrial appendage occluder in a canine model: the potential influence of the implantation technique on the healing response

Autor: Xiaoxia Wu, Dongxing Ma, Tao Wan, Yuezhi Meng, Yilong Chen, Yejia Shen, Wei Huang
Rok vydání: 2021
Předmět:
Zdroj: BMC cardiovascular disorders. 22(1)
ISSN: 1471-2261
Popis: Background Device-associated thrombus are potential causes for thromboembolic events post left atrial appendage closure (LAAC), and correlated with the complete endothelialization of the device surface. Our aim was to evaluate the endothelialization of LAMax LAAC™ occluder surface and analyze the potential influence of the implantation technique on the healing response. Methods A total of 29 healthy dogs (28.0 ± 3.7 kg) were implanted with the devices successfully after ensuring COVER signs was met (Concavity of the disc, Oversizing by 20–50%, Verifying position, Ensuring stability, Residual flow Results The mean diameters of LAA orifice measured by angiography and TEE were 19.0 ± 2.9 mm and 16.6 ± 2.9 mm (P Conclusions The good healing response and the optimal closure effect were observed using the LAMax device in a canine model by following the COVER implantation technique.
Databáze: OpenAIRE