Estimating the minimum important change in the 15D scores
Autor: | Soili Alanne, Tarja Vainiola, Risto P. Roine, Harri Sintonen, Pirjo Räsänen |
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Rok vydání: | 2014 |
Předmět: |
Male
Health Status Much Worse Quality of life Surveys and Questionnaires Statistical significance Linear regression Statistics Humans Medicine Operations management Hospital patients Finland Models Statistical business.industry Public Health Environmental and Occupational Health Regression analysis Middle Aged Assessment scale Confidence interval ROC Curve Research Design Quality of Life Female business Follow-Up Studies |
Zdroj: | Quality of Life Research. 24:599-606 |
ISSN: | 1573-2649 0962-9343 |
DOI: | 10.1007/s11136-014-0787-4 |
Popis: | To facilitate the interpretation of empirical results produced by the 15D, a generic, preference-based instrument for measuring health-related quality of life (HRQoL), a subjective five-category global assessment scale (GAS) was used as an external anchor to determine the minimum important change (MIC) in the 15D scores. Altogether 4,903 hospital patients representing sixteen disease entities and having the 15D score at baseline repeated the HRQoL assessment at 6 months after treatment and answered the question: compared to the situation before treatment, my overall health status is now (1) much better, (2) slightly better, (3) much the same, (4) slightly worse, (5) much worse. Regression analysis was used to estimate the MIC for improvement/deterioration, defined as the lower/upper limit of 99.9 % confidence interval of the regression coefficient, standardized for baseline HRQoL, for categories (2) and (4), respectively, and confirmed by ROC curve analysis. The limits or intervals for classifying the changes of 15D scores into GAS categories were >.035 for (1), .015–.035 for (2),>−.015 and |
Databáze: | OpenAIRE |
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