Survey on Haemoglobin Variants, β-Thalassaemia, Glucose-6-Phosphate Dehydrogenase Deficiency and Haptoglobin Types in Turkish People Living in Manavgat, Serik and Boztepe (Antalya)
| Autor: | Günçağ Dinçol, Muzaffer Aksoy, Sakir Erdem |
|---|---|
| Rok vydání: | 1980 |
| Předmět: |
Adult
Male congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Turkey Haemoglobin s Turkish Hemoglobins Abnormal Hemoglobin Sickle Population Haemoglobin variants Internal medicine Genetics medicine Humans education Genetics (clinical) Aged education.field_of_study Haptoglobins biology Haptoglobin Genetic Variation Middle Aged medicine.disease language.human_language Beta-thalassaemia Genetics Population Glucosephosphate Dehydrogenase Deficiency Endocrinology Biochemistry biology.protein language Thalassemia Female Hemoglobin geographic locations Glucose-6-phosphate dehydrogenase deficiency |
| Zdroj: | Human Heredity. 30:3-6 |
| ISSN: | 1423-0062 0001-5652 |
| DOI: | 10.1159/000153079 |
| Popis: | 135 Turks living in the vicinity of Antalya, a Turkish city on the Mediterranean coast, were studied for haemoglobin variants, beta-thalassaemia G-6-PD deficiency and haptoglobin types. The incidence of Hb-S was 2.3%. 8 beta-thalassaemic individuals with increased Hb-A2 and patient with 1 sickle cell-beta2-thalassaemia disease were found. The incidence of beta-thalassaemia with increased Hb-A2 was 6.7% and that of G-6-PD deficiency was 5.4%. The distribution of haptoglobin types in these people was very similar to that found in Turkish people in general; the only exception was the presence of Hp O in 2 individuals without haemolytic disorder. Gene frequencies of Hp1 and Hp2 were 0.26 and 0.7p4, respectively. |
| Databáze: | OpenAIRE |
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