The First Isoenzymatic Characterizations of the Leishmania Strains Responsible for Cutaneous Leishmaniasis in the Area of Annaba (Eastern Algeria)

Autor: Francine Pratlong, Roukaya Mansouri, Boussad Hamrioui, Fatma Bachi, J. P. Dedet
Přispěvatelé: Université Badji Mokhtar Annaba (UBMA), Centre National de Référence des Leishmanioses [CHRU Montpellier] (CNR-L), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université de Montpellier (UM), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud]), Institut Pasteur d'Algérie, Réseau International des Instituts Pasteur (RIIP), CHU Nafissa Hamoud [Hussein Dey], This work is a part of a research project funded by the Agence Nationale pour le Developpement de la Recherche en Santé (ANDRS).
Rok vydání: 2012
Předmět:
Zdroj: The Open Conference Proceedings Journal
The Open Conference Proceedings Journal, 2012, 3 (suppl 2-M2), pp.6-11. ⟨10.2174/1876326X01203020006⟩
ISSN: 2210-2892
DOI: 10.2174/2210289201203020006
Popis: International audience; The epidemiological situation of cutaneous leishmaniasis in the region of Annaba (North Eastern Algeria) is explored for the first time. During a clinical survey carried out in the Annaba Hospital between 2004 and 2008, the parasitological study of lesions has revealed 259 positive cases (43.31%). Isoenzymatic identification of 16 strains isolated showed the presence of three Leishmania species and four zymodemes. The hypothesis of the presence of L. infantum is confirmed with two zymodemes, MON-1 and MON-24. The unexpected presence of L. major MON-25 certifies the substantial extension of this zoonotic form to the North. The isolation of L.killicki, whose presence was unsuspected, reiterated the interest of eco-epidemiological analysis of households affected by the disease. Moreover, it is a new zymodeme never isolated so far, the MON-306.
Databáze: OpenAIRE