Acid Secretion From Birth to Adulthood
| Autor: | John T. Boyle |
|---|---|
| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent medicine.drug_class Proton-pump inhibitor Gastroenterology Gastric Acid Internal medicine medicine Humans Dosing Reflux esophagitis Child Adverse effect Esophagitis Peptic Esophageal disease business.industry Stomach Reflux Infant Gestational age Proton Pump Inhibitors Proton Pumps Anti-Ulcer Agents medicine.disease Treatment Outcome medicine.anatomical_structure Child Preschool Pediatrics Perinatology and Child Health Gastroesophageal Reflux Female business |
| Zdroj: | Journal of Pediatric Gastroenterology and Nutrition. 37:S12-S16 |
| ISSN: | 0277-2116 |
| Popis: | All infants, including premature infants as young as 24 weeks' gestational age, are able to maintain an intragastric pH below 4 from the first day of life. By 24 weeks, maximal acid output approaches that in adults. In adult studies, proton pump inhibitors (PPIs) are highly effective in relieving reflux symptoms and healing reflux esophagitis. Studies are needed to evaluate PPI efficacy and appropriate dosing in infants and children. Consequences such as hypergastrinemia, bacterial overgrowth, and other potential adverse events associated with long-term PPI use also warrant evaluation in the pediatric population. |
| Databáze: | OpenAIRE |
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