Helicobacter pylori Infection and Peptic Ulcer Disease in Patients with Liver Cirrhosis

Autor: Sang-Hoon Park, Gwang Ho Baik, Dong Joon Kim, Choong Kee Park, Myoung Kuk Jang, Sung Jung Kim, Jin Bong Kim, Hak Yang Kim, Myung Seok Lee, Tae Ho Hahn
Rok vydání: 2008
Předmět:
Zdroj: The Korean Journal of Internal Medicine
ISSN: 1226-3303
DOI: 10.3904/kjim.2008.23.1.16
Popis: Background/Aims We investigated the prevalence and relationship of peptic ulcer disease and Helicobacter pylori infection to liver cirrhosis. Methods We examined 288 patients with liver cirrhosis, 322 patients with non-ulcer dyspepsia, and 339 patients with peptic ulcer disease. Rapid urease test and Wright-Giemsa staining were used for diagnosis of H. pylori infection. Results The prevalence of peptic ulcer disease in patients with cirrhosis was 24.3%. The prevalence of peptic ulcer disease in patients with cirrhosis divided into Child-Pugh classes A, B, and C was 22.3%, 21.0%, and 31.3%, respectively (p>0.05). The prevalence of H. pylori infection in the patients with cirrhosis, non-ulcer dyspepsia, and peptic ulcer without chronic liver disease were 35.1%, 62.4%, and 73.7%, respectively (p0.05). The prevalence of H. pylori infection in patients with hepatitis virus-related liver cirrhosis and in the patients with alcohol-related liver cirrhosis was 42.5% and 22.0%, respectively (p
Databáze: OpenAIRE