Pilocytic Astrocytomas: Well-Demarcated Magnetic Resonance Appearance Despite Frequent Infiltration Histologically
| Autor: | Kevin J. Coakley, Glenn S. Forbes, Patrick J. Kelly, John Huston, Bernd W. Scheithauer |
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| Rok vydání: | 1995 |
| Předmět: |
Adult
Male medicine.medical_specialty Pathology Adolescent Central nervous system Astrocytoma Central nervous system disease White matter Edema Glioma Parenchyma medicine Humans Child Aged Retrospective Studies medicine.diagnostic_test Brain Neoplasms business.industry Infant Magnetic resonance imaging General Medicine Middle Aged medicine.disease Spinal cord Magnetic Resonance Imaging medicine.anatomical_structure Child Preschool Female Radiology medicine.symptom Tomography X-Ray Computed business |
| Zdroj: | Mayo Clinic Proceedings. 70:747-751 |
| ISSN: | 0025-6196 |
| Popis: | Objective To determine the magnetic resonance imaging (MRI) characteristics of pilocytic astro-cytomas and to correlate them with the histopathologic findings. Material and Methods MRI examinations and histopathologic findings in 56 patients with pilocytic astrocytomas were retrospectively reviewed. In 38 patients, findings on MRI were compared with those on computed tomography. Results The tumors occurred at all levels of the central nervous system, including the spinal cord. The intracranial tumors were periventricular (73%) or periaqueductal (9%). All tumors were typical pilocytic astrocytomas and were grade 1 on the basis of the World Health Organization classification. At operation, they were often circumscribed and cystic. Radiologically, the tumors were well demarcated (96%), had benign morphologic features, and almost always showed enhancement (94 %). Conclusion MRI of pilocytic astrocytomas typically demonstrated a relatively large, sharply demarcated periventricular mass with pronounced contrast enhancement but minimal or no associated edema. Often, the tumors were cystic on MRI. Despite the well-demarcated appearance grossly and on MRI, pathologic review showed that many of these tumors (64%) infiltrated the surrounding parenchyma, particularly the white matter. |
| Databáze: | OpenAIRE |
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