Is partial ablation appropriate for benign thyroid nodules? A retrospective study with long-term follow-up after microwave ablation
Autor: | Jie Yu, Wenjia Cai, Sisi Liu, Zhiyu Han, Zhigang Cheng, Xiaoling Yu, Ping Liang, Fangyi Liu |
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Rok vydání: | 2021 |
Předmět: |
Thyroid nodules
Cancer Research medicine.medical_specialty microwave Physiology Long term follow up medicine.medical_treatment Thermal ablation benign nodule thyroid 030218 nuclear medicine & medical imaging thermal ablation 03 medical and health sciences 0302 clinical medicine Physiology (medical) Medical technology medicine Humans Thyroid Nodule R855-855.5 Microwaves Retrospective Studies ultrasound business.industry Ultrasound Thyroid Microwave ablation Retrospective cohort study medicine.disease Ablation humanities Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Catheter Ablation Radiology business Follow-Up Studies |
Zdroj: | International Journal of Hyperthermia, Vol 38, Iss 1, Pp 923-930 (2021) |
ISSN: | 1464-5157 0265-6736 |
Popis: | Objective This retrospective study aimed to investigate the efficacy and safety of partial ablation (PA) for benign thyroid nodules (BTNs) using microwave ablation (MWA) in a long-term follow-up. Materials and methods Between February 2015 and April 2019, 236 patients with 236 BTNs (maximum diameter ≥2 cm) treated with ultrasound-guided MWA were enrolled. Contrast-enhanced ultrasound (CEUS) was performed within 3 d after ablation to determine whether there was residual tissue according to which the patients were assigned PA or complete ablation (CA). The volume reduction ratio (VRR) and complications were evaluated during follow-up. Results Eighty-two patients were enrolled in the PA group, and 154 were enrolled in the CA group. Both groups achieved continuous reductions in nodule volume and increases in VRR within 2 years after ablation. Although the VRR of the PA group at 4 years was lower than that of the CA group (65.54 vs. 95.08%; p.05). Conclusions Both PA and CA were safe and effective in reducing the volumes of BTNs in the long-term follow-up. For nodules with a large initial volume and dangerous location, PA with a small amount of residual tissue may be acceptable. |
Databáze: | OpenAIRE |
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