Advances in biomarkers of biliary tract cancers
| Autor: | Baobing Yin, Jun Hu |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Vascular Endothelial Growth Factor A
0301 basic medicine Oncology medicine.medical_specialty Personalized treatment Gastroenterology 03 medical and health sciences Tumor Biomarkers 0302 clinical medicine Internal medicine Biomarkers Tumor medicine Humans Diagnostic biomarker Gallbladder cancer Pharmacology Biliary tract neoplasm Biliary tract cancer business.industry General Medicine medicine.disease Biliary Tract Neoplasms 030104 developmental biology Biliary tract 030220 oncology & carcinogenesis Biomarker (medicine) Mitogen-Activated Protein Kinases business Signal Transduction |
| Zdroj: | Biomedicine & Pharmacotherapy. 81:128-135 |
| ISSN: | 0753-3322 |
| DOI: | 10.1016/j.biopha.2016.02.045 |
| Popis: | Tumor biomarkers can be applied for early diagnosis or precise treatment, thereby leading to personalized treatment and better outcomes. Biliary tract cancers (BTCs) are a group of cancers that occurs in different locations and have different clinical or genetic properties. Though the incidence of BTCs is rare, BTCs are among the most lethal cancers in the world and all have very low 5-year survivals. Lack of efficient early diagnostic approaches or adjuvant therapies for BTCs are main reasons. These urge us to broaden the researches into BTC biomarkers. Although few progresses of diagnostic biomarkers for BTCs have been achieved, there are still some advances in prognostic, predictive and therapeutic areas. In this review, we will focus on these achievements. |
| Databáze: | OpenAIRE |
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