Evalutation of the scintigraphic technique for detecting bone metastases in 100 breast cancer patients
Autor: | Alberto Marabini, Annamaria Molino, Franco Benini, Maria Carla Capelli, Pier Giorgio Giorgetti, T. Savarin, Luciano Vettore, Massimo Zamboni, Antonietta Bassetto |
---|---|
Jazyk: | angličtina |
Rok vydání: | 1979 |
Předmět: |
Cancer Research
medicine.medical_specialty Radiography chemistry.chemical_element Bone Neoplasms Breast Neoplasms Scintigraphy Technetium 030218 nuclear medicine & medical imaging Metastasis 03 medical and health sciences 0302 clinical medicine Breast cancer Humans Medicine Diagnostic Errors Radionuclide Imaging medicine.diagnostic_test business.industry Total body General Medicine medicine.disease Oncology Bone scintigraphy chemistry 030220 oncology & carcinogenesis Radiological weapon Female Radiology business |
Popis: | In an attempt to evaluate the utility of bone scintigraphy for the diagnosis and follow-up of skeletal metastases, radioisotopic scan (total body) by 99mTc has been performed on 100 patients suffering from breast cancer in various stages. The radiographic control followed the scan on the basis of clinical or scintigraphic suspicion of bone lesions. Twenty-one patients showed metastases by scan, and in all but 2 the radiography was concordantly positive; in 22 subjects scintigraphy and radiology demonstrated non-malignant lesions. Both scan and radiology were used to explore 169 metastatic localizations, with concordant results in 45% of the sites; however, 7% of the sites with discordant results became positive for metastasis by radiology some months after the scan positivity. The false–negative results were more frequent in the radiographic study (27%) than with the scintigraphic scan (21%). The latter technique was unable to detect osteoblastic lesions in particular. The scintigraphic test also gave reliable results in the follow-up procedure, frequently anticipating the radiological modifications of metastatic lesions. In conclusion, bone scan often appears to be more accurate and precocious than the roentgengraphic test in the detection and the follow-up of skeletal metastatic lesions; it suggests the utility of the bone scan as a preliminary test, which allows a more rational use of the radiology. |
Databáze: | OpenAIRE |
Externí odkaz: |