The Difference in the Mucus Organization Between the Small and Large Intestine and Its Protection of Selected Natural Substances. A Review
| Autor: | Zuzana Maková, Z. Faixová, Renáta Szabóová, Elena Piešová |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Veterinary medicine layer 0402 animal and dairy science Zoology 04 agricultural and veterinary sciences General Medicine respiratory system Biology intestinum protection 040201 dairy & animal science Mucus Natural (archaeology) 03 medical and health sciences fluids and secretions 030104 developmental biology medicine.anatomical_structure mucin mucus SF600-1100 medicine additives Large intestine |
| Zdroj: | Folia Veterinaria, Vol 62, Iss 4, Pp 48-55 (2018) |
| ISSN: | 2453-7837 |
| DOI: | 10.2478/fv-2018-0037 |
| Popis: | The mucus layer of the intestinal tract plays an important role of forming the front line of innate host defense. Recent studies have suggested that the involvement of feeding natural additives on protection/prevention/promotion of mucus production in the intestinal environment is beneficial. The goblet cells continually produce mucins for the retention of the mucus barrier under physiological conditions, but different factors (e. g. microorganisms, microbial toxins, viruses, cytokines, and enzymes) can have profound effects on the integrity of the intestinal epithelium covered by a protective mucus. The intestinal mucus forms enterocytes covered by transmembrane mucins and goblet cells produce by the secreted gel-forming mucins (MUC2). The mucus is organized in a single unattached mucus layer in the small intestine and in two mucus layers (inner, outer) in the colon. The main part of the review evaluates the effects of natural additives/substances supplementation to stimulate increased expression of MUC2 mucin in the intestine of animals. |
| Databáze: | OpenAIRE |
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