Treatment of Kleine-Levin Syndrome With Intranasal Photobiomodulation and Methylene Blue
| Autor: | Michael Hamper, Jay Lombard, Paolo Cassano |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Psychiatry
medicine.medical_specialty business.industry i-pbm General Engineering medicine.disease Pediatrics Dermatology red light kleine-levin syndrome intranasal photobiomodulation Neuropsychiatric disorder Neurology Kleine–Levin syndrome Etiology medicine Genetic predisposition methylene blue Nasal administration Red light business After treatment |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| DOI: | 10.7759/cureus.18596 |
| Popis: | Kleine-Levin syndrome (KLS) is a rare neuropsychiatric disorder, characterized by recurrent episodes of idiopathic hypersomnia, and cognitive and behavioral abnormalities, such as memory loss and child-like language. There is no definitive etiology for KLS; however, there are hypotheses of genetic predisposition, autoimmune mechanisms, and abnormal thalamic and hypothalamic functioning. Similarly, there is no definitive treatment for KLS as one method may be beneficial for one patient and not for another. We present a case of KLS in a patient who has no clinical improvement in symptoms with a variety of treatments. The parents of the patient agreed to attempt a trial of intranasal photobiomodulation (i-PBM) with red light, in combination with methylene blue (MB). The patient showed remission of the KLS episode following treatment with no further KLS episodes reported after treatment. |
| Databáze: | OpenAIRE |
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