Plasmodium falciparum transmission rate and selection for drug resistance: a vexed association or a key to successful control?
Autor: | S. Mharakurwa |
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Rok vydání: | 2004 |
Předmět: |
Plasmodium falciparum
Drug Resistance Indoor residual spraying Disease Drug resistance Insect Control law.invention Antimalarials law parasitic diseases medicine Animals Humans Malaria Falciparum Control (linguistics) Selection (genetic algorithm) biology Chloroquine medicine.disease biology.organism_classification Insect Vectors Infectious Diseases Transmission (mechanics) Immunology Parasitology Malaria |
Zdroj: | International Journal for Parasitology. 34:1483-1487 |
ISSN: | 0020-7519 |
DOI: | 10.1016/j.ijpara.2004.10.011 |
Popis: | While malaria eradication campaigns once adopted a combination of vector control and chemotherapy to overcome the disease, today's opinion on the matter is equivocal. So what has changed? This paper reviews some of the confusing hypotheses on the relationship between Plasmodium falciparum transmission and levels of drug resistance. New field evidence showing variations of in vivo chloroquine resistance in relation to indoor residual spraying and natural endemicity patterns, is considered with a view to how these phenomena implicate on control. |
Databáze: | OpenAIRE |
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