Discharged COVID-19 patients testing positive again for SARS-CoV-2 RNA: A minireview of published studies from China
| Autor: | Zhiyong Han, Stanley R Terlecky, Fortunato Battaglia |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
China Reviews Respiratory tract Review Pathogenesis medicine.disease_cause Asymptomatic Virus 03 medical and health sciences 0302 clinical medicine Virology Internal medicine Pandemic Medicine Humans 030212 general & internal medicine Asymptomatic Infections False Negative Reactions Virus classification Coronavirus Shedding business.industry Reverse Transcriptase Polymerase Chain Reaction SARS-CoV-2 RNA COVID-19 Reactivation Reverse transcriptase Patient Discharge Infectious Diseases COVID-19 Nucleic Acid Testing RNA Viral 030211 gastroenterology & hepatology medicine.symptom business Infection |
| Zdroj: | Journal of Medical Virology |
| ISSN: | 1096-9071 |
| Popis: | In the ongoing coronavirus disease 2019 (COVID-19) pandemic, one potential cause of concern is that some discharged COVID-19 patients are testing positive again for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. To better understand what is happening and to provide public health policy planners and clinicians timely information, we have searched and reviewed published studies about discharged patients testing positive again for the SARS-CoV-2 RNA. Our search found 12 reports, all of which described patients in China. Our review of these reports indicates the presence of discharged patients who remain asymptomatic but test positive. However, it is unclear whether they are contagious because a positive reverse transcriptase - polymerase chain reaction (RT- PCR) test does not necessarily indicate the presence of replicating and transmissible virus. Our review suggests the need for timely, parallel testing of different samples, including, for example, fecal specimens, from COVID-19 patients before and after they are discharged from hospitals. |
| Databáze: | OpenAIRE |
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