Combined Effects of Sucrose and Fluoride on Experimental Caries and on the Associated Microbial Plaque
| Autor: | Prathip Phantumvanit, Carl A. Ostrom, T. Koulourides, Frances Hickman |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Adult
0301 basic medicine Sucrose Dental Plaque Dentistry Dental Caries Fluorides 03 medical and health sciences chemistry.chemical_compound Dental Enamel Solubility 0302 clinical medicine stomatognathic system Humans Bovine enamel Food science Child Dental Enamel General Dentistry Bacteria Enamel paint Chemistry Experimental model business.industry In vitro exposure 030206 dentistry stomatognathic diseases 030104 developmental biology Human mouth visual_art visual_art.visual_art_medium business Fluoride Tooth Calcification |
| Zdroj: | Journal of Dental Research. 56:212-221 |
| ISSN: | 1544-0591 0022-0345 |
| DOI: | 10.1177/00220345770560030401 |
| Popis: | In an experimental model, slabs of sound and presoftened bovine enamel were worn in the human mouth for seven days except for periodic removal for in vitro exposure to experimental variables. Supplementation with 3% sucrose for 10 minutes, four times daily for seven days yielded predicted levels of experimental caries. Parallel exposure to 3% sucrose containing 100 ppm fluoride sharply reduced or negated the resultant caries in originally sound enamel, and reversed the simulated pre-experimental caries in most samples of presoftened enamel. Serial layers of test enamel surfaces showed high levels of fluoride accumulated in the originally sound enamel, and even higher levels in the presoftened enamel that had been supplemented with sucrose-fluoride solution. Quantitation of the plaque microbial flora showed that the fluoride ion exerted no detectable influence. Consistent with the findings in previous studies, some correlation appeared to exist between the degree of experimental caries and that proportion of total plaque that was comprised of S salivarius, S mutans, or lactobacilli. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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