[18F]Fluorocholine PET/CT False Positive: Foreign Body Reaction Mimicking Low-Grade Glioma Progression

Autor: Teodoro Rudolphi-Solero, Eva María Triviño-Ibáñez, Jose Pablo Martínez-Barbero, Nicolás Cordero-Tous, Clara Eurgenia Chamorro-Santos, Antonio Rodríguez-Fernández, Manuel María Gómez-Río
Rok vydání: 2022
Předmět:
Popis: A right frontoparietal neoplastic lesion was found in a young-aged patient with analgesic refractory headache. Surgical resection was performed, and the pathologist analysis turned out a cellular ependymoma with signs of anaplasia. In the follow-up, a MRI showed a suspicious lesion, so a [18F]Fluorocholine PET/CT was performed. An increased uptake was described in the right parietal region on the margin of residual cystic lesion. The patient got a complete resection which was confirmed later by MR. In the pathology analysis, a focally congestive cerebral parenchyma with a central histiocytic reaction to foreign body area was described. Foreign body reaction in brain tissue is a very rare immune response that has not been well studied. Haemostatic material has been reported as a possible trigger of this response in other organs and could be detected by [18F]FDG PET/CT. Following the experience of the current case report, [18F]Fluorocholine PET/CT could also show a false positive related to foreign body reaction.
Databáze: OpenAIRE