5-Methylcoumaranones from Mutisia friesiana and their bioactivity
| Autor: | Juana Rosa de la Fuente, Marta S. Maier, Carmen Ines Viturro |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: |
Mutisia friesiana
Staphylococcus aureus Antifungal Agents Argentina Pharmaceutical Science Microbial Sensitivity Tests Biology Asteraceae Bioactivity Analytical Chemistry Drug Discovery Botany Nuclear Magnetic Resonance Biomolecular Antibacterial agent Benzofurans Pharmacology Folk medicine Plants Medicinal Molecular Structure Otras Ciencias Químicas Organic Chemistry Ciencias Químicas Complementary and alternative medicine Molecular Medicine Cladosporium CIENCIAS NATURALES Y EXACTAS |
| DOI: | 10.1021/np0304058 |
| Popis: | In addition to the known mutisicoumaranones A (1) and B (2), the methanolic extract of the aerial parts of the shrub Mutisia friesiana afforded two new 5-methylcoumaranones, mutisicoumaranones C (3) and D (4). Their structures were elucidated by spectroscopic methods. 13C NMR data for mutisicoumaranones A and B are reported for the first time. All compounds showed antifungal activity against the phytopathogenic fungus Cladosporium cucumerinum and bactericidal activity against Staphylococcus aureus. The presence of 5-methylcoumaranones A-D is biosynthetically related to 5-methylcoumarins and phenolic derivatives previously isolated from M. friesiana. Fil: Viturro, Carmen Ines. Universidad Nacional de Jujuy. Facultad de Ingeniería; Argentina Fil: de la Fuente, Juana Rosa. Universidad Nacional de Salta. Facultad de Ciencias Exactas; Argentina Fil: Maier, Marta Silvia. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Orgánica; Argentina |
| Databáze: | OpenAIRE |
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