Antibacterial Activity of Soaps Indigenously Made in Gombe Metropolis, Nigeria
| Autor: | Kasim Salihu Izebe, Peters Oladosu, M. I. Aboh, Y. A. Umar, M. T. Adamu, A. Salawudeen |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Pharmacology integumentary system Contact time Pseudomonas aeruginosa Microorganism 030106 microbiology liquid soaps microorganisms solid soaps time kill kinetics mic Biology lcsh:RZ409.7-999 medicine.disease medicine.disease_cause biology.organism_classification 03 medical and health sciences Staphylococcus aureus medicine Food science Klebsiella pneumonia Antibacterial activity lcsh:Miscellaneous systems and treatments Escherichia coli Bacteria |
| Zdroj: | Journal of Natural Remedies, Vol 18, Iss 4, Pp 122-130 (2018) |
| ISSN: | 2320-3358 0972-5547 |
| DOI: | 10.18311/jnr/2018/22434 |
| Popis: | As part of Federal Government policy on Small Medium Enterprises in Nigeria, a lot of small scale businesses have sprung up including soap making industries using indigenous contents. The ability of indigenously manufactured soaps to remove germs and dirt is paramount. An in vitro evaluation of antibacterial activity of twelve randomly collected indigenously made soaps in Gombe metropolis, Nigeria was conducted using agar well diffusion method against strains of reference microbes viz; Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Bacillus subtilis and Klebsiella pneumonia being human skin bacteria, followed by time kill kinetic assay to determine the pharmaco-dynamics of active soaps against susceptible test organisms. The results obtained show that six of the soaps exhibited antibacterial activity with varying degree of zones of inhibition. S. aureus was the most susceptible amongst the organisms while E. coli and P. aeruginosa were the least susceptible microbes. The time kill kinetic assay shows that the bactericidal effect of the soaps is dose and contact time dependent as the susceptible organisms were eliminated after 8 h exposure. The antibacterial activities exhibited by these soaps suggest them as potential candidate in bio-prospecting for antibacterial. |
| Databáze: | OpenAIRE |
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