How to Improve Chemical Synthesis of Laminaribiose on a Large Scale
| Autor: | Jean-Claude Yvin, Daniel Plusquellec, Frank Jamois, F. Le Goffic, Vincent Ferrieres |
|---|---|
| Přispěvatelé: | inconnu, Inconnu, Institut des Sciences Chimiques de Rennes (ISCR), Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA), Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes), Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS) |
| Rok vydání: | 2008 |
| Předmět: |
chemistry.chemical_classification
[CHIM.ORGA]Chemical Sciences/Organic chemistry 010405 organic chemistry Scale (chemistry) Acetal Glycosidic bond 010402 general chemistry 01 natural sciences Chemical synthesis 0104 chemical sciences chemistry.chemical_compound chemistry Organic chemistry Lewis acids and bases Laminaribiose ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Open Glycoscience Open Glycoscience, Bentham Open, 2008, pp.19-24. ⟨10.2174/1875398100801010019⟩ Open Glycoscience, 2008, pp.19-24. ⟨10.2174/1875398100801010019⟩ |
| ISSN: | 1875-3981 |
| Popis: | Laminaribiose, which is the simplest -(1,3)-glucan, is one of the most powerful agents able to increase germi- nation. Its chemical synthesis was revised in detail starting from peracylated donors and easily available glucofuranose protected by acetal groups in the presence of appropriated catalyst and/or promoter. We particularly focused our attention on the nature of the Lewis acid generally required in glycosidic couplings. Finally, an interesting scale-up was performed which allowed us to prepare laminaribiose on a kilogram scale. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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