Cultivated maitake mushroom demonstrated functional food quality as determined by in vitro bioassays
| Autor: | Muraleedharan G. Nair, Chuan-Rui Zhang, Gary L. Mills, Amila A. Dissanayake |
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| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Naproxen Antioxidant Erogosterol peroxide (PubChem CID: 5351516) Ergosteryl 3-β-d-glucopyranoside (PubChem CID: 44176397) Glyceride medicine.medical_treatment 1-Oleoyl-3-linoleoylglycerol (PubChem CID: 71751316) Medicine (miscellaneous) 01 natural sciences Lipid peroxidation 03 medical and health sciences chemistry.chemical_compound Cerebroside B (PubChem CID: 10010147) Functional food medicine TX341-641 Ergosterol (PubChem CID: 444679) Food science Grifola frondosa Mushroom Nutrition and Dietetics biology Nutrition. Foods and food supply 010405 organic chemistry Chemistry 1-Oleoyl-2-linoleoyl-3-palmitoylglycerol (PubChem CID: 14299219) 0104 chemical sciences 030104 developmental biology biology.protein Cyclooxygenase Food Science medicine.drug |
| Zdroj: | Journal of Functional Foods, Vol 44, Iss, Pp 79-85 (2018) |
| ISSN: | 1756-4646 |
| Popis: | Cultivated fruiting body of Grifola frondosa is a culinary and medicinal mushroom. In this study, we investigated its functional food value. Extracts of its fruiting body afforded known compounds, glycerides (1 and 2), sterols (3–5), a glucosylceramide (6), a α-glucose dimer (7), a phospholipid (8) and α-glucans as elucidated by spectroscopic methods. This is the first report of compounds 2, 5 and 8 from the fruiting body of G. frondosa. Most of the pure isolates showed antiinflammatory and antioxidant activities as demonstrated by inhibitions of cyclooxygenase enzymes (COX-1 and -2) and lipid peroxidation (LPO), respectively. Compounds 1, 4, and 5 from this mushroom inhibited COX enzymes at 100 µg/mL similar to aspirin, naproxen and ibuprofen, the non-steroidal antiinflammatory drugs (NSAIDs) used as controls in the assays. |
| Databáze: | OpenAIRE |
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