Case report: Neoadjuvant systemic therapy for melanoma
| Autor: | Natiya Gabuniya, Ankur Khajuria, Jenny L. C. Geh, Daniah Alsaadi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
medicine.medical_treatment Neoadjuvant systemic therapy Disease Systemic therapy Advanced metastatic melanoma Lesion 03 medical and health sciences 0302 clinical medicine Case report medicine Skin cancer Chemotherapy business.industry Melanoma Treatment options General Medicine medicine.disease 030220 oncology & carcinogenesis 030211 gastroenterology & hepatology Surgery Histopathology Radiology medicine.symptom business |
| Zdroj: | Annals of Medicine and Surgery |
| ISSN: | 2049-0801 |
| Popis: | We report a case of rapidly enlarging metastatic melanoma in 45-year-old White male following primary resection of thin melanoma five years ago. Location and large size of the lesion possessed significant risk of complications from surgery, therefore provided a challenge in treatment options. Neoadjuvant targeted chemotherapy was commenced and resulted in a significant reduction in size of the lesion, which allowed subsequent safe surgical resection with no residual disease on histopathology results. This case provides a good example of successful utilization of neoadjuvant systemic therapy in advanced metastatic melanoma. Highlights • Outline of advanced metastatic melanoma presentation. • Successful treatment with neoadjuvant therapy that aided surgical resection and achieved disease free results on follow up. • Overall improved survival and remission of patient with advanced disease. |
| Databáze: | OpenAIRE |
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