Fusion imaging to evaluate the radiographic anatomical relationship between primary tumors and local recurrences in retroperitoneal soft tissue sarcoma
| Autor: | Sonja Janssen, Holger Haubenreisser, Peter Hohenberger, Helene Weigl, Jens Jakob, Nikolaos Vassos, Anna Simeonova-Chergou, Frederik Wenz |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Radiography Pilot Projects 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine medicine Image Processing Computer-Assisted Retroperitoneal sarcoma Humans Dicom viewer Prospective Studies Retroperitoneal Neoplasms Aged Image fusion business.industry Soft tissue sarcoma Sarcoma Middle Aged medicine.disease Prognosis Primary tumor Magnetic Resonance Imaging Oncology 030220 oncology & carcinogenesis Anatomical relationship Surgery Female Radiology Neoplasm Recurrence Local business Tomography X-Ray Computed Follow-Up Studies |
| Zdroj: | Surgical oncology. 34 |
| ISSN: | 1879-3320 |
| Popis: | Background Local recurrence (LR) of retroperitoneal soft tissue sarcoma (RPS) is a common and life-threatening event. The evaluation of the exact anatomical patterns of local recurrence might help to improve local treatment in RPS. Methods Of our local database we extracted ten patients with LR of RPS with axial MRI and/or CT datasets of the primary tumor (PT) and the LR. Using the Osirix DICOM viewer Version v.3.9.4 64-bit (Pixmeo, Geneva, Switzerland) we performed a three-step fusion algorithm consisting of: a) 3-point co-registration of the axial datasets depicting the PT and the LR using three abdominal landmarks b) re-orientation of the datasets and c) image fusion. We evaluated the feasibility of this technique with regard to categorizing the localization of LR as within or distant from the PT. Results Fusion imaging was feasible in seven out of ten patients. In the other three patients anatomical shifting of organs after surgery led to a relevant mismatch of anatomical landmarks and impeded interpretation of the fused images. In five of seven patients with successful fusion imaging, local recurrences were located within the anatomical borders of the primary tumor, in two out of seven patients local recurrences were distant to the primary. Conclusions Fusion imaging of primary tumors and local recurrences is feasible in most patients with RPS. Most local recurrences occurred within the anatomical localization of the primary tumor. For further investigations validation of the technique in larger patient cohorts is required. |
| Databáze: | OpenAIRE |
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