Monomeric form of C-reactive protein in the assessment of the residual inflammatory cardiovascular risk in patients with subclinical carotid atherosclerosis

Autor:	I. S. Melnikov, S. G. Kozlov, O. A. Pogorelova, M. I. Tripoten, O. S. Saburova, L. Sh. Khamchieva, Yu. N. Avtaeva, M. D. Zvereva, L. V. Prokofieva, T. V. Kuznetsova, O. A. Guseva, T. V. Balakhonova, Z. A. Gabbasov
Rok vydání:	2022
Předmět:	Carotid Artery Diseases Inflammation Male Cholesterol LDL Middle Aged Atherosclerosis Carotid Intima-Media Thickness C-Reactive Protein Cardiovascular Diseases Heart Disease Risk Factors Risk Factors Humans Female Cardiology and Cardiovascular Medicine Biomarkers
Zdroj:	Kardiologiia. 62:24-30
ISSN:	2412-5660 0022-9040
DOI:	10.18087/cardio.2022.7.n2137
Popis:	Aim To study the relationship between monomeric C-reactive protein (mCRP) and the progression of asymptomatic carotid atherosclerosis in patients with a moderate risk for cardiovascular diseases (CVD) as assessed with the SCORE model.Material and methods The study included 80 men and women aged 53.1±5.8 years assigned to the category of a moderate risk for CVDs by the SCORE model with a low-density lipoprotein cholesterol (LDL-C) level of 2.7–4.8 mmol/l and asymptomatic, hemodynamically insignificant (Results A concentration of LDL-C Conclusion According to the results of 7-year follow-up, the plasma concentration of mCRP was significantly higher in patients with an increased number of ASPs than in patients without this increase. An increased level of mCRP may indicate a higher inflammatory risk of CVD.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41997e280c2a5044a7437fbe773c4424 https://doi.org/10.18087/cardio.2022.7.n2137 Zobrazit plný text záznamu