High consumption of ultra-processed food may double the risk of subclinical coronary atherosclerosis: the Aragon Workers’ Health Study (AWHS)
| Autor: | Pilar Guallar-Castillón, Carolina Donat-Vargas, Fernando Civeira, Belén Moreno-Franco, Martín Laclaustra, Helena Sandoval-Insausti, Henry Montero-Salazar |
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| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty lcsh:Medicine Disease Coronary calcium Coronary Artery Disease 03 medical and health sciences 0302 clinical medicine Risk Factors Internal medicine Prevalence Medicine Humans 030212 general & internal medicine Coronary atherosclerosis Subclinical infection Subclinical coronary atherosclerosis Consumption (economics) Nutritional epidemiology business.industry lcsh:R General Medicine Middle Aged Cross-sectional cohort study Atherosclerosis Ultra-processed food Cross-Sectional Studies Quartile Fast Foods Female Agatston score business 030217 neurology & neurosurgery Research Article |
| Zdroj: | BMC Medicine BMC Medicine, Vol 18, Iss 1, Pp 1-11 (2020) |
| ISSN: | 1741-7015 |
| Popis: | BackgroundUltra-processed food (UPF) consumption, which is increasing worldwide, has recently been associated with an increased risk of death and cardiovascular disease. We aimed to assess whether consumption of UPF is directly associated with subclinical coronary atherosclerosis in middle-aged men.MethodsA computed tomography scan was performed on 1876 men from the Aragon Workers’ Health Study, recruited from January 2011 to December 2014, to assess coronary calcium. All participants were free of coronary heart disease. Dietary intake was collected by a validated 136-item semi-quantitative food frequency questionnaire. UPF was defined according to the NOVA classification. Associations between consumption of total energy-adjusted UPF and Coronary Calcium Agatston Score (CACS)—categorized into CACS of 0, > 0 and ResultsNo coronary calcium was detected in 60.2% of the participants, whereas 10.2% had a CACS ≥ 100. A significant dose-response association was observed between energy-adjusted UPF consumption and the risk of having a CACS ≥ 100, when compared with those in the lowest CACS categories (CACS of 0 together with CACS > 0 and ptrend .005.ConclusionIn this middle-aged worker’s sample, approximately 500 g/day of UPF consumption was associated with a 2-fold greater prevalence of subclinical coronary atherosclerosis than consuming only 100 g/day, independently of total energy intake and other well-established cardiovascular risk factors. |
| Databáze: | OpenAIRE |
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