The Role of Vitamin D in Brain Health: A Mini Literature Review
| Autor: | Syeda S Jaffery, Sheraz Anjum, Ibrar Anjum, Zarak Samoo, Muniba Fayyaz |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Antioxidant medicine.medical_treatment autism vitamin D deficiency 03 medical and health sciences 0302 clinical medicine Internal medicine Diabetes mellitus medicine Vitamin D and neurology Internal Medicine Dementia Depression (differential diagnoses) Calcium metabolism business.industry General Engineering Endocrinology/Diabetes/Metabolism medicine.disease schizophrenia 030104 developmental biology Endocrinology vitamin d deficiency Neurology Schizophrenia depression diabetes mellitus business 030217 neurology & neurosurgery dementia |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Vitamin D is vital for our body as it regulates calcium homeostasis and maintains bone integrity. In this article, we will discuss how vitamin D aids in the function of neuronal and glial tissue and the many health consequences in a person with vitamin D deficiency. Some of the effects of vitamin D deficiency that will be discussed include the development of dementia caused by the increase of cerebral soluble and insoluble amyloid-β (Aβ) peptides and a decrease of its anti-inflammatory/antioxidant properties, the link to depression by a reduction of the buffering of increased calcium in the brain, and vitamin D deficiency in expecting mothers linking to the development of autism and schizophrenic-like disorders, hypoxic brain injury, and other mental illnesses. Lastly, we will discuss how vitamin D deficiency is linked to the development of diabetes mellitus, its role in neuronal development and a decrease of microglial inflammatory function leading to increased brain infections. |
| Databáze: | OpenAIRE |
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