Gamma knife radiosurgery of meningiomas in the cavernous sinus region
| Autor: | L. Janoušková, Gabriela Simonova, Vilibald Vladyka, Roman Liscak, Josef Vymazal |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male medicine.medical_specialty Optic tract medicine.medical_treatment Radiosurgery Central nervous system disease Meningioma medicine Humans Aged Aged 80 and over medicine.diagnostic_test business.industry Brain Neoplasms Cavernous Sinus Meningioma Interventional radiology Middle Aged medicine.disease Magnetic Resonance Imaging Surgery Treatment Outcome Cavernous sinus Cavernous Sinus Female Neurology (clinical) Neurosurgery Radiology business Follow-Up Studies |
| Zdroj: | Acta neurochirurgica. 141(5) |
| ISSN: | 0001-6268 |
| Popis: | For 6 years (1992-1998) we have treated 67 patients with cavernous sinus meningioma using the Leksell gamma knife in the Hospital Na Homolce, Prague. The age of the patients ranged between 19-82 years, median 57 years. Radiosurgery was the primary treatment in 64.2% of the patients, in the rest a microsurgical resection preceded. The volume of the tumour ranged from 0.9-31.4 cm3, median 7.8 cm3. The meningioma was distant from the optic tract in 58% of the cases, in 12% of the cases there was a contact with the tumour and the optic tract without its compression and in 30% of the cases there was a compression of the optic tract caused by the meningioma. The dose to the tumour margin ranged from 10-14 Gy, median 12 Gy. The follow up was available in 53 patients, in intervals of 2-60 months, median 19 months. There was no change in the tumour volume in 48% of the cases, in 52% of the cases a decrease of the tumour volume occurred. No increase of the tumour volume was observed. Clinical symptoms and signs improved in 35.8% of the patients, temporary morbidity was 3.8%. The mortality of the treatment was zero. Hitherto, the results of gamma knife radiosurgery of cavernous sinus meningioma have proved its safety and efficiency, although long term experience with a large group of patients is missing. Advances in neuroradiology and radiosurgical technique have allowed us to treat tumours with a closer contact to the optic tract and nerves compared with the past. |
| Databáze: | OpenAIRE |
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