Synthesis by anodic-spark deposition of Ca- and P-containing films on pure titanium and their biological response
| Autor: | Oksana Banakh, Tony Journot, Pierre-Antoine Gay, Joël Matthey, Catherine Csefalvay, Oleg Kalinichenko, Olha Sereda, Mira Moussa, Stéphane Durual, Lyubov Snizhko |
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| Rok vydání: | 2016 |
| Předmět: |
Materials science
Biocompatibility Simulated body fluid General Physics and Astronomy chemistry.chemical_element 02 engineering and technology Electrolyte 010402 general chemistry 01 natural sciences law.invention law Chemical composition Electrolysis Anodizing Metallurgy Surfaces and Interfaces General Chemistry 021001 nanoscience & nanotechnology Condensed Matter Physics ddc:617.6 0104 chemical sciences Surfaces Coatings and Films Anode chemistry Chemical engineering 0210 nano-technology Titanium |
| Zdroj: | Applied Surface Science Applied Surface Science, Vol. 378 (2016) pp. 207-215 |
| ISSN: | 0169-4332 |
| DOI: | 10.1016/j.apsusc.2016.03.161 |
| Popis: | The purpose of this study is to characterize the anodised layers formed on titanium by anodic spark deposition in an electrolyte containing Ca and P ions (Ca3(PO4)2). The oxidation experiments were performed at different periods of time and using different concentrations of electrolyte. The influence of the process parameters (time of electrolysis and electrolyte concentration) on the surface morphology and chemical composition of the anodised layers was studied. It has been found that it is possible to incorporate Ca and P into the growing layer. A response of the anodised layers in a biological medium was evaluated by their immersion in a simulated body fluid. An enrichment of titanium and a simultaneous loss of calcium and phosphorus in the layer after immersion tests indicate that these coatings should be bioresorbable in a biological medium. Preliminary biological assays were performed on some anodized layers in order to assess their biocompatibility with osteoblast cells. The cell proliferation on one selected anodized sample was assessed up to 21 days after seeding. The preliminary results suggest excellent biocompatibility properties of anodized coatings. Further experiments assessing cell morphology proliferation differentiation and gene expression are needed to comfort these encouraging preliminary results. |
| Databáze: | OpenAIRE |
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