Premature birth impacts bolus size and shape through nursing in infant pigs
| Autor: | Laura E. Bond, Alexis M Myrla, Francois D. H. Gould, Christopher J. Mayerl, Rebecca Z. German, Bethany M. Stricklen |
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| Rok vydání: | 2019 |
| Předmět: |
Time Factors
Sus scrofa Population Video Recording Gestational Age Article 03 medical and health sciences 0302 clinical medicine Bolus (medicine) Nursing Swallowing 030225 pediatrics Animals Medicine education Video recording education.field_of_study business.industry Extramural Gestational age medicine.disease Animals Suckling Deglutition Animals Newborn Term Infant Premature birth Fluoroscopy Pediatrics Perinatology and Child Health Premature Birth business 030217 neurology & neurosurgery |
| Zdroj: | Pediatric research |
| ISSN: | 1530-0447 0031-3998 |
| DOI: | 10.1038/s41390-019-0624-0 |
| Popis: | Background The formation of a bolus of food is critical for proper feeding function, and there is substantial variation in the size and shape of a bolus prior to a swallow. Preterm infants exhibit decreased abilities to acquire and process food, but how that relates to their bolus size and shape is unknown. Here, we test two hypotheses: (1) that bolus size and shape will differ between term and preterm infants, and (2) bolus size and shape will change longitudinally through development in both term and preterm infants. Methods To test these hypotheses, we measured bolus size and shape in preterm and term infant pigs longitudinally through nursing using high-speed videofluoroscopy. Results Preterm infant pigs swallowed smaller volumes of milk. Although term infants increased the amount of milk per swallow as they aged, preterm infants did not. These changes in bolus volume were also correlated with changes in bolus shape; larger boluses became more elongate as they better filled the available anatomical space of the valleculae. Conclusion These results suggest that preterm birth reduces the ability of preterm pigs to increase bolus size as they grow, affecting development in this fragile population. These results highlight that studies on term infant feeding may not translate to preterm infants. |
| Databáze: | OpenAIRE |
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