Monounsaturated fatty acids-rich diets in hypercholesterolemic-growing rats
| Autor: | Natalia Juiz, Christian E. Lezón, Fima Lifshitz, Estefania Alsina, Laura Schreier, Elisa Vanesa Macri, Valeria Zago, Patricia Mónica Boyer, Silvia María Friedman, Patricia Rodriguez |
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| Rok vydání: | 2015 |
| Předmět: |
Male
medicine.medical_specialty food.ingredient Saturated fat Hypercholesterolemia Blood lipids Soybean oil Adipose capsule of kidney Fatty Acids Monounsaturated food Bone Density Internal medicine medicine Animals Plant Oils Sunflower Oil Food science Rats Wistar Olive Oil Triglycerides Atherogenic diet medicine.diagnostic_test Chemistry Sunflower oil Lipids Diet Rats Soybean Oil Disease Models Animal Endocrinology Adipose Tissue Liver Diet Atherogenic Bone mineral content lipids (amino acids peptides and proteins) Lipid profile Food Science |
| Zdroj: | International Journal of Food Sciences and Nutrition. 66:400-408 |
| ISSN: | 1465-3478 0963-7486 |
| DOI: | 10.3109/09637486.2015.1025719 |
| Popis: | The effects of replacing dietary saturated fat by different monounsaturated fatty acid (ω-9MUFA) sources on serum lipids, body fat and bone in growing hypercholesterolemic rats were studied. Rats received one of the six different diets: AIN-93G (control, C); extra virgin olive oil (OO) + C; high-oleic sunflower oil (HOSO) + C or atherogenic diet (AT) for 8 weeks; the remaining two groups received AT for 3 weeks and then, the saturated fat was replaced by an oil mixture of soybean oil added with OO or HOSO for 5 weeks. Rats consuming MUFA-rich diets showed the highest body fat, hepatic index and epididymal, intestinal and perirenal fat, and triglycerides. T-chol and non-HDL-chol were increased in HOSO rats but decreased in OO rats. Bone mineral content and density were higher in both OO and HOSO groups than in AT rats. This study casts caution to the generalization of the benefits of MUFA for the treatment of hypercholesterolemia. |
| Databáze: | OpenAIRE |
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