Comparison of two carbohydrate intake strategies to improve glucose control during exercise in adolescents and adults with type 1 diabetes
| Autor: | Corinne Suppère, Andréanne Fortin, Nadine Taleb, Marie-Béatrice Saade, Azadeh Shohoudi, Mélanie Henderson, Laurent Legault, Lucas Goulet-Gélinas, Virginie Messier, Sémah Tagougui, Rémi Rabasa-Lhoret |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty Time Factors Adolescent Glucose control Endocrinology Diabetes and Metabolism Physical activity Medicine (miscellaneous) 030209 endocrinology & metabolism Glycemic Control 030204 cardiovascular system & hematology Hypoglycemia 03 medical and health sciences 0302 clinical medicine Internal medicine Dietary Carbohydrates medicine Humans Exercise Glycemic Carbohydrate intake Glycated Hemoglobin Type 1 diabetes Cross-Over Studies Nutrition and Dietetics business.industry Age Factors Quebec Middle Aged Carbohydrate medicine.disease Crossover study Diabetes Mellitus Type 1 Treatment Outcome Endocrinology Female Cardiology and Cardiovascular Medicine business Biomarkers |
| Zdroj: | Nutrition, Metabolism and Cardiovascular Diseases. 31:1238-1246 |
| ISSN: | 0939-4753 |
| DOI: | 10.1016/j.numecd.2020.12.011 |
| Popis: | Background and aims During aerobic physical activity (PA), hypoglycemia is common in people with type 1 diabetes (T1D). Few studies have compared the effectiveness of different carbohydrate (CHO) intake strategies to prevent PA-induced hypoglycemia. Our objective was to compare the efficacy of two CHO intake strategies, same total amount but different CHO intake timing, to maintain glucose levels in the target range (4.0–10.0 mmol/L) during PA in people with T1D. Methods and results An open-label, randomized, crossover study in 33 participants (21 adults; 12 adolescents). Participants practiced 60 min PA sessions (ergocyle) at 60% VO2peak 3.5 h after lunch comparing an intake of 0.5 g of CHO per kg of body weight applied in a pre-PA single CHO intake (SCI) or in a distributed CHO intake (DCI) before and during PA. The percentage of time spent in glucose level target range during PA was not different between the two strategies (SCI: 75 ± 35%; DCI: 87 ± 26%; P = 0.12). Hypoglycemia ( Conclusions In people living with T1D, for a 60 min moderate aerobic PA in the post-absorptive condition, a 0.5 g/kg CHO intake helped most participants maintain acceptable glycemic control with both strategies. No clinically significant difference was observed between the SCI and DCI strategies. ClinicalTrials.gov Identifier: NCT03214107 (July 11, 2017). |
| Databáze: | OpenAIRE |
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