Plasma atrial natriuretic peptide in cardiac transplant recipients. A prospective study
| Autor: | Terje Forslund, Svein Simonsen, Fridtjov Riddervold, Frej Fyhrquist, Erik Myhre, Tor Frøysaker, Ilkka Tikkanen |
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| Rok vydání: | 1988 |
| Předmět: |
Cardiac function curve
Adult Male medicine.medical_specialty Adolescent Vasopressins medicine.medical_treatment Hemodynamics chemistry.chemical_compound Atrial natriuretic peptide Internal medicine Renin–angiotensin system Renin Internal Medicine medicine Humans Prospective Studies Aldosterone Heart transplantation Heart Failure business.industry Myocardium Middle Aged medicine.disease Transplantation chemistry Heart failure cardiovascular system Cardiology Heart Transplantation Female business hormones hormone substitutes and hormone antagonists Atrial Natriuretic Factor Follow-Up Studies |
| Zdroj: | Acta medica Scandinavica. 224(1) |
| ISSN: | 0001-6101 |
| Popis: | Cardiac transplantation in 10 patients with congestive heart failure resulted in reduction of high plasma concentrations of atrial natriuretic peptide (ANP), preoperatively five-fold above normal, to a level two-fold above normal, which was maintained throughout a 12-week follow-up period. Cardiac function was normalized in all patients. Transient increases in plasma ANP, in four cardiac recipients 3-10-fold their basal levels, could neither be related to rejection episodes nor to cardiac dysfunction, but rather to signs of fluid and sodium retention. High plasma ANP levels in cardiac transplant recipients suggest that the capacity to secrete ANP is preserved in the transplanted heart. |
| Databáze: | OpenAIRE |
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