Twin-twin transfusion syndrome: an ethics-based and evidence-based argument for clinical research
| Autor: | William D. Fraser, David Stamilio, Thomas R. Moore |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Pediatrics
medicine.medical_specialty Laser Coagulation Evidence-based practice business.industry MEDLINE Obstetrics and Gynecology Fetofetal Transfusion Twins Monozygotic Evidence-based medicine Scientific literature Ultrasonography Prenatal law.invention Clinical trial Randomized controlled trial Pregnancy law Humans Medicine Scientific consensus Female Observational study Medical physics Pregnancy Multiple business |
| Zdroj: | American Journal of Obstetrics and Gynecology. 203:3-16 |
| ISSN: | 0002-9378 |
| Popis: | Aspects of twin-twin transfusion syndrome (TTTS) diagnosis, treatment alternatives, and research opportunities were considered during a consensus conference that was held by the North American Fetal Therapy Network in 2009. A 3-member scientific consensus panel gathered data from expert conference presentations, postconference communications, and comprehensive scientific literature database searches to develop recommendations for TTTS diagnosis, therapy, and research. The panel recommends retaining the Quintero staging system until a superior system has been validated appropriately. It concludes that there is normative equipoise to justify the performance of randomized clinical trials to identify the optimal treatment strategy for mild TTTS. Recommendations for the design and conduct of clinical trials and observational studies are also provided. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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