Pregnancy results after ovum donation following one to seven embryo transfers
| Autor: | Fotini Dimitriadou, Themis Mantzavinos, Katerina Arvaniti, Katerina Voutsina, Nikos Kanakas, Demetrios Rizos |
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| Rok vydání: | 1996 |
| Předmět: |
Infertility
Adult medicine.medical_specialty Uterus Fertilization in Vitro Abortion Endometrium Pregnancy medicine Humans Retrospective Studies Gynecology Oocyte Donation Obstetrics business.industry Obstetrics and Gynecology Middle Aged medicine.disease Embryo Transfer Embryo transfer Abortion Spontaneous medicine.anatomical_structure Reproductive Medicine In utero Female business Infertility Female Embryo quality |
| Zdroj: | Fertility and sterility. 66(5) |
| ISSN: | 0015-0282 |
| Popis: | Objective To determine whether failure to achieve pregnancy after repeated ET after ovum donation was due to an endometrial defect or to the embryo quality. Design Retrospective data analysis. Setting A private infertility center. Patient(s) Four hundred sixty-seven donors (513cycles) undergoing IVF donating oocytes to 266 recipients (423cycles). Intervention(s) Hormonal endometrial preparation with increasing dosages of valerate E 2 (2, 4, and 6mg) and 100mg of P. Main Outcome Measure(s) Pregnancy rates (PRs) and abortion rates in patients undergoing one to seven ETs after ovum donation. Result(s) Pregnancy rates in recipients that had one or two ETs were significantly higher (34.8%) compared with those of recipients having three or more ETs (15.1%). Abortion rates were significantly higher (54.5%) in recipients repeating more than three ETs than in the recipients having one or two ETs (29.1%). Conclusion(s) Recipients that had failed to establish a pregnancy after two ETs had a lower PR in successive attempts, possibly because of a defect of their endometrial lining. |
| Databáze: | OpenAIRE |
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