Visual acuity and scar size in eyes with age-related subfoveal choroidal neovascular lesions, 30 months after radiation therapy
| Autor: | August F. Deutman, W.A.J. van Daal, G. J. Bergink, Carel B. Hoyng, R.W.M. van der Maazen |
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| Přispěvatelé: | Ophthalmology |
| Jazyk: | angličtina |
| Rok vydání: | 1996 |
| Předmět: |
Male
Radiotherapy in senile macula degeneration Fovea Centralis medicine.medical_specialty Visual acuity genetic structures Fundus Oculi medicine.medical_treatment Visual Acuity Ionizing radiation Cicatrix Macular Degeneration Physiology (medical) Age related Ophthalmology Humans Medicine Fluorescein Angiography GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) Experimental radiotherapy and neuro-oncology Aged Aged 80 and over Neovascularization Pathologic Choroid business.industry Experimentele radiotherapie en neuro-oncologie medicine.disease Radiotherapie bij seniele maculadegenratie eye diseases Sensory Systems Radiation therapy Head and Neck Neoplasms Total dose Fluorescein angiogram Female sense organs medicine.symptom business Progressive disease Follow-Up Studies |
| Zdroj: | Documenta Ophthalmologica, 92, pp. 61-75 Documenta Ophthalmologica, 92, 61-75 Documenta Ophthalmologica, 92, 1, pp. 61-75 Documenta Ophthalmologica, 92, 61-75. Springer Netherlands |
| ISSN: | 0012-4486 |
| Popis: | Purpose: In a study to determin the effectiveness of ionizing radiation on the deterioration of visual acuity (VA) due to choroidal neovascularisation (CNV) the affected eyes of 10 patients were treated with a total dose of 24 Gy (6 Gy fractions). A special lens-sparing technique was used to avoid cataract development. During 30 months of follow-up the visual acuity (VA) and scar size (SS) of the treated eyes and fellow eyes of all 10 patients were evaluated.Results: After 30 months of follow-up 5 eyes showed a stable VA and fluorescein angiogram (FA) appearance. Concerning 4 out of 5 eyes with progressive disease, the 4 eyes treated with radiation therapy had better VA and smaller SS as compared with the untreated fellow eyes with exudative AMD.Conclusions: The results suggest that 24 Gy either stabilizes or delays the deleterious effects of CNV on the visual acuity. Until now no late side effects have been observed. |
| Databáze: | OpenAIRE |
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