Effects of Monounsaturated Enriched Sunflower Oil on CHD Risk Factors Including LDL Size and Copper-Induced LDL Oxidation
| Autor: | Emma Louise Ashton, James D. Best, Madeleine J. Ball |
|---|---|
| Rok vydání: | 2001 |
| Předmět: |
Adult
Blood Glucose Male medicine.medical_specialty food.ingredient Medicine (miscellaneous) Coronary Disease chemistry.chemical_compound food Risk Factors Internal medicine Dietary Carbohydrates medicine Humans Insulin Plant Oils Sunflower Oil Total fat Food science Risk factor Diet Fat-Restricted Triglycerides Cross-Over Studies Nutrition and Dietetics Chemistry Cholesterol Sunflower oil Cholesterol HDL Cholesterol LDL Middle Aged Carbohydrate Low fat diet Crossover study Lipoproteins LDL Postmenopause Endocrinology Female Lipid Peroxidation Energy Intake Chd risk Copper |
| Zdroj: | Journal of the American College of Nutrition. 20:320-326 |
| ISSN: | 1541-1087 0731-5724 |
| DOI: | 10.1080/07315724.2001.10719052 |
| Popis: | To compare the effects of a diet high in monounsaturated enriched sunflower oil and a low fat diet on CHD risk factors including in vitro Cu-induced LDL oxidation and LDL size, lipids, lipoproteins, glucose and insulin.A randomized crossover dietary intervention.Free living individuals.Fourteen healthy males 35 to 55 years of age and 14 healthy postmenopausal women 50 to 60 years of age completed the dietary intervention. Two subjects did not complete the study, and their data were not included.A low fat, high carbohydrate diet (22% to 25% of energy from total fat, 7% to 8% of energy from monounsaturated fat and 55% to 60% of energy from carbohydrate) was compared to a monounsatutated enriched sunflower oil (MO) diet (40% to 42% of energy from fat, with 26% to 28% from monounsaturated fat and 40% to 45% of energy from carbohydrate) in an isocaloric substitution. Each dietary period was one month.Total cholesterol, LDL cholesterol, triglycerides and glucose were not significantly different between the two diets. HDL cholesterol, HDL3 cholesterol and insulin were significantly higher on the MO diet, mean 7%, 7% and 17% higher respectively. Copper-induced LDL oxidation lag phase was significantly longer (mean 18%) after the MO diet compared to the low fat, high carbohydrate diet. LDL particle size was not significantly different.The significant increase in LDL oxidation lag phase and the significantly higher HDL cholesterol on the MO diet would be expected to be associated with a decrease in CHD risk. |
| Databáze: | OpenAIRE |
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