Bilateral anterior optic neuritis in adult measles infection without encephalomyelitis
| Autor: | Sumie Kawahara, Annabelle A. Okada, Masami Azuma, Yoshihiro Morimura |
|---|---|
| Rok vydání: | 2002 |
| Předmět: |
Adult
Pathology medicine.medical_specialty Optic Neuritis Encephalomyelitis Visual Acuity Optic disk Antibodies Viral Methylprednisolone Measles Measles virus medicine Maculopapular rash Humans Optic neuritis Glucocorticoids biology medicine.diagnostic_test Lumbar puncture business.industry medicine.disease biology.organism_classification Ophthalmology Immunoglobulin M Immunoglobulin G Optic nerve Female medicine.symptom business |
| Zdroj: | American Journal of Ophthalmology. 134:768-769 |
| ISSN: | 0002-9394 |
| DOI: | 10.1016/s0002-9394(02)01632-x |
| Popis: | PURPOSE: To describe anterior optic neuritis in adult measles infection. DESIGN: Interventional case report. METHODS: A 31-year-old woman presented with bilateral visual loss 6 days after the onset of maculopapular rash. Complete ophthalmic and neurologic examinations, radiologic studies, and lumbar puncture were performed. RESULTS: Visual acuities were counting fingers in both eyes, with bilateral optic disk hyperemia and swelling noted. Neurologic examination was unremarkable, and computed tomography and magnetic resonance imaging of the brain were normal. The cerebrospinal fluid (CSF) was devoid of white cells, although measles immunoglobulin M (IgM) antibodies were detected in both CSF and serum. Intravenous corticosteroids were administered, and clinical findings resolved within 1 month. A fall in serum IgM and a rise in serum IgG titers were observed. CONCLUSIONS: Although rare, optic neuritis in the absence of encephalomyelitis may occur in measles. Whether treatment is effective is unknown. |
| Databáze: | OpenAIRE |
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