Local Cerebral Blood Flow in Rats with Congenital Hydrocephalus
Autor: | R. M. Bucknall, H. K. Richards, H. C. Jones, John D. Pickard |
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Rok vydání: | 1993 |
Předmět: |
Inferior colliculus
Rats Mutant Strains Congenital hydrocephalus Reference Values Animals Medicine Tissue Distribution Tissue distribution business.industry Rats Inbred Strains Anatomy medicine.disease Pons Rats Hydrocephalus Neurology Cerebral blood flow Cerebrovascular Circulation Cerebellar cortex Anesthesia Reference values Autoradiography Neurology (clinical) Cardiology and Cardiovascular Medicine business |
Zdroj: | Journal of Cerebral Blood Flow & Metabolism. 13:531-534 |
ISSN: | 1559-7016 0271-678X |
DOI: | 10.1038/jcbfm.1993.69 |
Popis: | Local cerebral blood flow (LCBF) has been measured by [14C]iodoantipyrine quantitative autoradiography in H-Tx rats with inherited congenital hydrocephalus at 10, 21, and 30 days after birth. LCBF at 10 days was uniformly low in all ten brain regions studied and not significantly different between hydrocephalic and age-matched control rats. By 21 days LCBF had increased significantly in control rats. LCBF was significantly lower (−1 min−1 for hydrocephalics and from 100 to 183 ml 100 g−1 min−1 for controls. |
Databáze: | OpenAIRE |
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