Arterial oxygenation in anesthetized horses placed in a 5-degree reverse Trendelenburg position
| Autor: | Jane E. Quandt, Erik H. Hofmeister, H. Nicole Trenholme, Stephanie A. Kleine, Rachel A. Reed, Michele Barletta |
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| Rok vydání: | 2021 |
| Předmět: |
Male
040301 veterinary sciences Butorphanol Partial Pressure Pilot Projects Hypoxemia Head-Down Tilt 0403 veterinary science 03 medical and health sciences Acepromazine medicine Animals Anesthesia Horses Prospective Studies Propofol Tidal volume 030304 developmental biology 0303 health sciences Isoflurane General Veterinary business.industry 04 agricultural and veterinary sciences Arterial catheter Respiration Artificial Oxygen Arterial blood Pulmonary shunt Female Ketamine Blood Gas Analysis medicine.symptom business medicine.drug |
| Zdroj: | Research in Veterinary Science. 135:304-309 |
| ISSN: | 0034-5288 |
| Popis: | Low arterial oxygen is a common complication in anesthetized horses and placing the animal in reverse Trendelenburg (RT) position may treat hypoxemia. The objective of this study was to assess the arterial partial pressure of oxygen (PaO2) in horses placed in a 5-degree RT compared to horizontal (H) position. Client-owned healthy horses (n = 60) undergoing elective surgeries were enrolled in a randomized controlled clinical study. Horses were sedated with butorphanol, an α2-adrenoceptor agonist, ± acepromazine and induced with ketamine combined with a benzodiazepine, propofol, or guaifenesin. Anesthesia was maintained with isoflurane in oxygen with mechanical ventilation. Each group (RT and H) included 30 horses, 10 in each recumbency (dorsal, right and left lateral). Arterial blood gas analyses (aBG) were performed following arterial catheter placement then hourly. Time first-to-last aBG, changes in PaO2, dynamic compliance (Cdyn), estimated pulmonary shunt fraction (F-shunt), and alveolar dead space to tidal volume ratio (VD/VT) were evaluated with a 2-way analysis of variance. Statistical significance was set at p |
| Databáze: | OpenAIRE |
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