Factors Associated with Medication Adherence among Patients with Schizophrenia in Mekelle, Northern Ethiopia
| Autor: | Amha Teklu, Tadele Eticha, Adissu Alemayehu, Gebremedhin Solomon, Dagim Ali |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty Referral Adolescent Cross-sectional study medicine.medical_treatment lcsh:Medicine Medication Adherence Young Adult Pharmacotherapy Khat Risk Factors Internal medicine Surveys and Questionnaires medicine Prevalence Humans Young adult lcsh:Science Psychiatry Antipsychotic Adverse effect Multidisciplinary biology business.industry lcsh:R Awareness Middle Aged biology.organism_classification medicine.disease Prognosis Cross-Sectional Studies Schizophrenia Patient Compliance lcsh:Q Female Ethiopia business Research Article Antipsychotic Agents |
| Zdroj: | PLoS ONE PLoS ONE, Vol 10, Iss 3, p e0120560 (2015) |
| ISSN: | 1932-6203 |
| Popis: | Background Non-adherence to antipsychotic medication has a negative impact on the course of illness resulting in increased risk of relapse, rehospitalization and suicide, and increased costs to healthcare systems. The objective of this study was to investigate factors associated with medication adherence among patients with schizophrenia at Ayder Referral Hospital and Mekelle Hospital in Mekelle, Tigray region, Northern Ethiopia. Methods The study was a cross-sectional survey in which sociodemographic characteristics, drug attitudes, insight and side effects were measured and explored in terms of their relationship with medication adherence. A structured questionnaire as a data collection tool was used. Data were analyzed with the help of SPSS Version 20.0. Results A total of 393 patients participated, 26.5% were non-adherent to their antipsychotic medication. The factors significantly associated with better adherence were positive treatment attitudes (AOR = 1.40, 95% CI: 1.26, 1.55), fewer side effects (AOR = 0.97, 95% CI: 0.94, 0.99), awareness of illness (AOR = 1.44, 95% CI: 1.12, 1.85) and the ability to relabel symptoms (AOR = 1.57, 95% CI: 1.19, 2.07). However, khat chewers (AOR = 0.24, 95% CI: 0.09, 0.68), being illiterate (AOR = 0.13, 95% CI: 0.03, 0.47) and older age group (AOR = 0.03, 95% CI: 0.01, 0.16) were associated with less medication adherence. Conclusions A high prevalence of medication non-adherence was found among patients with schizophrenia. Intervention strategies focused on educating the patients to better understand the illness, medications and their potential side effects might be useful in improving adherence to antipsychotic medication treatment. |
| Databáze: | OpenAIRE |
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