Interactive effects of acute exercise and carbohydrate-energy replacement on insulin sensitivity in healthy adults

Autor:	Harry A Smith, Drusus Johnson-Bonson, Harry L. Taylor, Javier T. Gonzalez, Jonathan D Watkins, Jean-Philippe Walhin, Benjamin J Narang, Russell G Davies, Aaron Hengist, James A. Betts
Rok vydání:	2021
Předmět:	Blood Glucose Male Physiology Endocrinology Diabetes and Metabolism physical activity activité physique réalimentation insulin resistance énergie Morning disponibilité en glucides Nutrition and Dietetics glycaemic glycaemia General Medicine carbohydrate availability résistance à l’insuline Endurance Training Interactive effects Female glycémie glycémique energy Adult medicine.medical_specialty Physical activity deficit Young Adult Insulin resistance SDG 3 - Good Health and Well-being Endurance training Physiology (medical) Internal medicine medicine Dietary Carbohydrates Humans métabolisme Exercise refeeding Glycemic business.industry Insulin sensitivity Carbohydrate Glucose Tolerance Test medicine.disease glycemic Endocrinology déficit Physical Endurance Insulin Resistance business metabolism
Zdroj:	Johnson-Bonson, D, Narang, B J, Davies, R, Hengist, A, Smith, H, Watkins, J, Taylor, H, Walhin, J-P, Gonzalez, J & Betts, J 2021, ' Interactive effects of acute exercise and carbohydrate-energy replacement on insulin sensitivity in healthy adults ', Applied Physiology Nutrition and Metabolism, vol. 46, no. 10, pp. 1207-1215 . https://doi.org/10.1139/apnm-2020-1043
ISSN:	1715-5320
Popis:	This study investigated whether carbohydrate-energy replacement immediately after prolonged endurance exercise attenuates insulin sensitivity the following morning, and whether exercise improves insulin sensitivity the following morning independent of an exercise-induced carbohydrate deficit. Oral glucose tolerance and whole-body insulin sensitivity were compared the morning after 3 evening conditions, involving (1) treadmill exercise followed by a carbohydrate replacement drink (200 or 150 g maltodextrin for males and females, respectively; CHO-replace); (2) treadmill exercise followed by a non-caloric, taste-matched placebo (CHO-deficit); or (3) seated rest with no drink provided (Rest). Treadmill exercise involved 90 minutes at ∼80% age-predicted maximum heart rate. Seven males and 2 females (aged 23 ± 1 years; body mass index 24.0 ± 2.7 kg·m−2) completed all conditions in a randomised order. Matsuda index improved by 22% (2.2 [0.3, 4.0] au, p = 0.03) and HOMA2-IR improved by 10% (–0.04 [–0.08, 0.00] au, p = 0.04) in CHO-deficit versus CHO-replace, without corresponding changes in postprandial glycaemia. Outcomes were similar between Rest and other conditions. These data suggest that improvements to insulin sensitivity in healthy populations following acute moderate/vigorous intensity endurance exercise may be dependent on the presence of a carbohydrate-energy deficit. Novelty: Restoration of carbohydrate balance following acute endurance exercise attenuated whole-body insulin sensitivity. Exercise per se failed to enhance whole-body insulin sensitivity. Maximising or prolonging the post-exercise carbohydrate deficit may enhance acute benefits to insulin sensitivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4144b403ba1bd7dfe2faf9c3f0b46306 https://pubmed.ncbi.nlm.nih.gov/33831317 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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