Localization of the chromosomal breakpoints of the t(12;16) in liposarcoma to subbands 12q13.3 and 16p11.2
| Autor: | Magnus Eneroth, Sverre Heim, Nils Mandahl, Helena Willén, Felix Mitelman, Anders Rydholm, Karl Akke Alberts |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Genetic Markers Male Genetics Cancer Research medicine.medical_specialty Chromosomes Human Pair 12 Breakpoint Cytogenetics Chromosomal translocation Liposarcoma Middle Aged Biology medicine.disease Translocation Genetic Chromosome Banding Karyotyping Round cell medicine Humans Female Molecular Biology Chromosomes Human Pair 16 |
| Zdroj: | Cancer Genetics and Cytogenetics. 48:101-107 |
| ISSN: | 0165-4608 |
| DOI: | 10.1016/0165-4608(90)90222-v |
| Popis: | Short-term cultures of two myxoid liposarcomas and two mixed-type (myxoid and round cell) liposarcomas were cytogenetically analyzed. A t(12;16)(q13;p11) was present in three tumors, whereas the fourth had an unbalanced 12;16-translocation with breaks in 12q13 and 12q22, with loss of the 12q13-q22 segment, and in 16p11. In the two mixed liposarcomas, the breakpoints could be determined at subband level to 12q13.3 and 16p11.2. |
| Databáze: | OpenAIRE |
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