Leucocytoclastic vasculitis induced by prolonged exercise
| Autor: | A.H.B.M. Vermeulen, H.A.M. Neumann, J. C. J. M. Veraart, R. F. H. J. Hulsmans, M. Prins |
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| Jazyk: | angličtina |
| Rok vydání: | 1996 |
| Předmět: |
Pathology
medicine.medical_specialty biology medicine.diagnostic_test Erythema business.industry Physical exercise Dermatology Granulocyte medicine.disease Purpura medicine.anatomical_structure Immunoglobulin M Immunopathology Biopsy Immunology Innovation of diagnosis and therapy in clinical dermatology biology.protein Medicine Innovatie van diagnostische en therapeutische mogelijkheden in de klinische dermatologie medicine.symptom business Vasculitis GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) |
| Zdroj: | British Journal of Dermatology, 134, 915-918 British Journal of Dermatology, 134, 5, pp. 915-918 British Journal of Dermatology, 134, pp. 915-918 |
| ISSN: | 0007-0963 |
| Popis: | Many people develop skin symptoms after long-distance walks, but little is known about the aetiology of these. In this study we took 11 biopsies from 10 long-distance walkers who walked 80 km. All biopsies originated from purpuric lesions on the lower legs, which had appeared during walking. In all 11 specimens, signs of a leucocytoclastic vasculitis were present with leucocytoclasis, exocytosis of erythrocytes and a granulocyte/mononuclear perivascular infiltrate. Immunofluorescence investigations showed deposition of C3c in many specimens and immunoglobulin M in some. The occurrence of a leucocytoclastic vasculitis after prolonged exercise may be explained by the existence of an exercise altered cutaneous microcirculation, complement activation and an altered immune function. |
| Databáze: | OpenAIRE |
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