The asymptotic plurality rule for molecular sequences

Autor: Ewa Kubicka, Fred R. McMorris, William H. E. Day, Grzegorz Kubicki
Rok vydání: 1996
Předmět:
Zdroj: Mathematical and Computer Modelling. 23(3):27-42
ISSN: 0895-7177
DOI: 10.1016/0895-7177(95)00231-6
Popis: The asymptotic plurality rule, apl, is a consensus function which maps each profile P of length n (i.e., each sequence of n bases appearing at an aligned position of n molecules) to a set apl (P) of consensus results (i.e., ambiguity codes) that is a descriptive summary of P. Our main result is to characterize each consensus result X = apl(P) in terms of the frequencies with which the bases in P occur. We then use these characterizations to investigate features (e.g., strong consistency, length independence) of apl that researchers may find useful for the interpretation of apl's consensus results.
Databáze: OpenAIRE